Updated Oct 16, 2026, 2:28 PM ET
Annie Andrews
Democratic · 3 November 2026

Annie Andrews

Annie Andrews, a pediatrician living in Charleston and the Democratic nominee for US Senate in South Carolina, faces Republican appointee Darline Graham in the November 3, 2026, election.

Latest coverage

Live News

Recent media coverage for Annie Andrews.

  1. Democrat Annie Andrews running to flip a Senate seat in deep-red South Carolina

    Annie Andrews, a Democrat, is running to flip a Senate seat in South Carolina, a state traditionally dominated by Republicans. The news item highlights her candidacy and the challenge of winning in a deep-red state.

    ms.now
  2. President Trump plans tele-rally to boost support for Sen. Darline Graham

    Annie Andrews, a Democrat physician, is challenging incumbent Republican Sen. Lindsey Graham in South Carolina's Senate race.

    WCIV
  3. Democrats’ Chances of Retaking the Senate, According to Republican Polls

    The article discusses Republican polling in South Carolina for the U.S. Senate race featuring Annie Andrews (Democrat) against incumbent or challenging Republican candidate Darline Graham.

    Newsweek
  4. South Carolina Senate race: Graham, Andrews in close contest

    Annie Andrews is the Democratic candidate in South Carolina’s U.S. Senate race facing Republican incumbent-turned-appointee Darline Graham. The contest has been closer than expected in a largely Republican state.

    WJCL
  5. Darline Graham vs. Annie Andrews: What to know about South Carolina's US Senate race

    Background: Andrews is a pediatrician who markets her campaign on healthcare, affordability, and her experience with children and families.

    WCNC
More coverage 4
  1. Andrews, Graham clash over alleged family business ties to China

    In the South Carolina U.S. Senate race, Democrat Dr. Annie Andrews accused Republican Sen. Darline Graham of concealing her family’s business ties to China and profiting from China-related interests.

    WJCL
  2. President Trump may rally for Darline Graham in Greenville

    Summary: The article reports that President Donald Trump may travel to the Upstate of South Carolina to rally support for U.S. Senate candidate Darline Graham, who is in a tight race against Democrat Annie Andrews.

    The Post and Courier
  3. Democrats face possible headaches if they win the midterms

    In response to political pressure and attacks, Andrews released a direct-to-camera ad clarifying her stance: she does not support transgender girls’ participation in women’s sports and does not support gender-affirming…

    cnn.com
  4. SC US Senate campaign escalates on China, law enforcement

    South Carolina U.S. Senate race between Republican Sen. Lindsey Graham and Democratic challenger Dr. Annie Andrews heated up with dueling events over China, national security, and law enforcement.

    WYFF
Born
January 1, 1981
Birthplace
Paducah, Kentucky
Education
University of Dayton (bachelor's degree)
University of Cincinnati College of Medicine (MD)
Medical University of South Carolina (master's degree in clinical research)

Biography & Campaign Analysis

Background

Born Anne Elizabeth Lintzenich in Paducah, Kentucky, in 1981, Andrews grew up in Indianapolis, Indiana.

She completed undergraduate studies at the University of Dayton and medical school at the University of Cincinnati, and later added a clinical research master's from the Medical University of South Carolina (MUSC).

After a pediatric residency in Cincinnati, she moved to South Carolina's Lowcountry in 2009 and spent 14 years as a pediatric hospitalist at MUSC Children's Hospital in Charleston, where she was also a professor of pediatrics.

Following the 2018 Parkland high school shooting, she joined the advocacy group Moms Demand Action and began clinical research on preventing firearm injuries among children.

Career

In November 2021 Andrews entered the race for South Carolina's 1st congressional district, her first campaign for public office. Unopposed for the Democratic nomination in June 2022, she lost the November 8, 2022, general election to Representative Nancy Mace, 42.5% to 56.5%.

In April 2023 she launched a political action committee called "Their Future. Our Vote", and she resigned from MUSC in June 2023. By mid-2025 she was working part-time as a pediatrician at Children's National Hospital in Washington, D.C., while living in Charleston.

2026 race

Andrews announced her Senate candidacy on May 29, 2025, to challenge Republican Lindsey Graham, and won the Democratic primary on June 9, 2026, taking 61.5% against Brandon Brown, a former Paine College administrator. Graham, who won the Republican nomination the same day, died on July 11, 2026.

His sister, Darline Graham, was appointed to the seat and won the Republican nomination in an August 25 runoff against Representative Ralph Norman with 52.5% of the vote.

Andrews and Graham meet in the general election on November 3, 2026, and the winner is expected to become the first woman South Carolina has elected to the Senate.